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G6PDi-1 B
CAS No. 2457232-14-1
G6PDi-1 B( —— )
Catalog No. M37586 CAS No. 2457232-14-1
G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 49 | Get Quote |
|
| 5MG | 76 | Get Quote |
|
| 10MG | 132 | Get Quote |
|
| 25MG | 266 | Get Quote |
|
| 50MG | 426 | Get Quote |
|
| 100MG | 614 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameG6PDi-1 B
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NoteResearch use only, not for human use.
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Brief DescriptionG6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.
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DescriptionG6PDi-1 is a reversible and non-competitive glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC50 of 0.07 μM for human G6PD. G6PDi-1 depletes NADPH most strongly in lymphocytes. G6PDi-1 markedly decreases inflammatory cytokine production in T cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetDehydrogenase
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RecptorDehydrogenase
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Research Area——
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Indication——
Chemical Information
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CAS Number2457232-14-1
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Formula Weight284.34
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Molecular FormulaC14H12N4OS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (175.85 mM; Ultrasonic )
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SMILESO=C1CCCCc2nc(Nc3csc(c3)C#N)ncc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jonathan M Ghergurovich, et al. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. Nat Chem Biol. 2020 Jul;16(7):731-739.?
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